CRCI²NA - Nantes - Angers Cancer and Immunology Research Center
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Discover our teams
Immunomodulation of the Tumor Microenvironment and Immunotherapy of Thoracic Cancers - Team 1
Nuclear Oncology - Team 2
Innate Immunity and Cancer - Team 4
Design and application of innovative loco-regional Treatments in Glioblastoma - Team 5
Signaling in Oncogenesis Angiogenesis and Permeability - Team 6
Stress Adaptation and Tumor Escape - Team 7
Extracellular vesicles based intercellular communication and their Application for Therapy
Integrative Cancer Genomics -Team 8
Chromatin and Transcriptional Deregulation in Pediatric Bone Sarcoma - Team 9
Plasticity of Ecosystem from the Tumor after Radiotherapy - Team 10
Molecular Vulnerabilities of Tumor Escape in mature B-cell Malignancies - Team 11
Manipulation of Lymphocytes for Immunotherapy - Team 12
Our key figure
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330more than 330 members in the lab
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55more than 55 projects
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800more than 800 scientific papers edited
About the CRCI²NA
The CRCI²NA (Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes Angers in French) was created in January 2022 by the INSERM, the CNRS, the University of Nantes, and the University of Angers as a result of a structuration of oncology and immuno-cancerology research that was initiated in 1979.
The CRCI2NA is committed to promoting gender equality, diversity, and inclusion as well as embracing environmental responsibility for an ecological and societal transition. These initiatives are reflected in its organization, operations, and communication.
This Center is composed of 12 research teams dedicated to the analysis of tumors as ecosystems composed of distinct cell types, linked by cooperative or competitive relationships. The overall project of the CRCI²NA is to explore the interactions and dynamic changes of tumor ecosystems during tumor progression as well as the mechanisms of dissemination in response to treatments.
The CRCI2NA is committed to promoting gender equality, diversity, and inclusion as well as embracing environmental responsibility for an ecological and societal transition. These initiatives are reflected in its organization, operations, and communication.
This Center is composed of 12 research teams dedicated to the analysis of tumors as ecosystems composed of distinct cell types, linked by cooperative or competitive relationships. The overall project of the CRCI²NA is to explore the interactions and dynamic changes of tumor ecosystems during tumor progression as well as the mechanisms of dissemination in response to treatments.
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More specifically, the CRCI²NA teams focus on the death/survival decisions of malignant cells as well as their molecular evolution, the reactivity of immune cells and the cooperativity of stromal cells. They combine a broad spectrum of expertise, including cancer genomics and computational biology, cell and molecular biology, cell models (3D and murine), immuno-oncology and imaging.This multi-scale approach allows the identification of diagnostic and predictive tools, the deciphering of treatment resistance mechanisms and the design of innovative therapies and theranostic approaches, based on the molecular, phenotypic and radiomic specificities of each cancer. Spread over five sites, the CRCI²NA is the largest cancer research center in the Grand Ouest region.
Catherine Philippe Juin
Pellat-Deceunynck Director
Deputy Director
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Mis à jour le 16 September 2024.